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¿ä¾à Leprosy is a chronic infectious and granulomatous disease caused by Mycobacterium leprae. It is
treated with a multidrug therapy (MDT), which is consisted of dapsone, rifampicin, and clofazimine.
However, there were relapsed leprosy associated with various predisposing factors; persisting
organism, multiple involved skin lesions and nerves, HIV infection, monotherapy, inadequate and
irregular therapy. Early or late relapses were observed in leprosy. Early onset relapses may occur
due to insufficient treatment, and late relapses are probably with persistent bacilli and drug
resistant organisms. Herein, we report on an interesting case of a 78-year-old man presented
with relapsed leprosy associated with ulcerative skin lesions. The patient was diagnosed with
lepromatous leprosy about 40 years ago, and he was treated with dapsone monotherapy and MDT.
Our case is thought to have occurred due to persistent bacilli related to irregular therapy.

▪ Key words : Leprosy, Relapse
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