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제목 나병의 신경병변에 대한 하이드록소코바마이드(비타민 B12) 효과
저자 이경덕 소속 국립소록도병원
년도 2008 41
2 번호 3
시작페이지 17 끝페이지 22
첨부 3 이경덕.pdf
요약 95 patients in Sorokdo national hospital injected 1-5mg Hydroxocobalamin
(5mg/2ml/1ample) in 5-7 days/week, duration 6.4 months, average age 71.6 years old.
Effects are
1) softening of hand movement(22/95), early effect,
2) improving of motor function (8/95)
3) sensory function(8/95)
4) sweating (3/95)
5) neuropathic pain and headache(neuralgia-like) (7/95)
6) jaw and hand tremor (7/95)
7) no response (41/95)
8) side effect (1/95)
Leprosy is demyelinating peripheral neuropathy, Vitamin B12 effects on myelin, but unkown it's mechnism.
Vitamin B12 improve nerve function impairments in leprosy, especially neuropathic pain and tremor, which lead to deformities and disabilities.

Key words : Leprosy, Nerve function impairment, Neuralgia, Tremor,
Hydroxocobalamin(Vitamin B12)
내용