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제목 한센병 신환자 및 재발환자 6예
저자 김종필, 김연실 소속 한국한센복지협회 연구원
년도 2008 41
1 번호 3
시작페이지 37 끝페이지 46
첨부 3.김종필,김연실.pdf
요약 In 2007, we find 3 new cases and 3 relapse cases, diagnosis by the clinical finding, skin smear, skin biopsy, lepromin test, ELISA for PGL-I antibody, and DNA-PCR.
The results obtained were summarized as follows:
1. In 3 new cases, 2 Koreans are 70 and 79 years old, one foreigner (Filipino) is 38 years old, mean BI is 2.8, and mean O.D. of PGL-I antibody is 0.22, and numbers of TTC repeat are 10(Korean), 11(Korean), and 12(Filipino), and of GACATC repeats are 4(2 Koreans) and 3(1 foreigner/ Filipino). All new cases have no mutation of folP1 & rpoB gene.
2. In 3 relapse cases, the mean age is 56.8, mean BI is 5.6+,and mean O.D. of PGL-I antibody is 0.70, and numbers of TTC repeat are 11(2 cases), and 12(1 case), and of GACATC repeats are 4(all 3 Koreans). Among 3 relapse cases, 2 cases have the mutation of folP1 gene and 2cases have the mutationo frpoB gene, especially one case have the mutation of both folP1 & rpoB gene.


Key Words : Leprosy, New case, Relapse.
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