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제목 |
한센병균 감염 모형으로서 Zebrafish의 유용 가능성 |
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저자 |
김종필*,최혜영,조상래 |
소속 |
한국한센복지협회 연구원, 이화의대 피부과학교실, 연세의대 미생물학교실 |
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년도 |
2006 |
권 |
39 |
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호 |
1 |
번호 |
2 |
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시작페이지 |
37 |
끝페이지 |
48 |
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첨부 |
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요약 |
The zebrafish emerged as a new model of developmental research and infection. Recently zebrafish were used for various mycobacterial infection studies. In this study, we investigated a possibility of the zebrafish as an infection model of Mycobacterium leprae infection. We injected Mycobacterium leprae (105/30 l) to the peritoneum of zebrafish. After 4 weeks, we found two fish evident to the subsistence and multiplication of Mycobacterium leprae, among total 25 fish. This study thus demonstrates that zebrafish may become an animal model for M. leprae infection.
Key word: infection model, zebrafish, Mycobacterium leprae
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내용 |
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