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HOME > ÇÐȸ°£Ç๰ >
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A Case of Erythema Nodosum Leprosum with Various Systemic Manifestations Developed in Borderline-lepromatous Patient after Delivery |
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Suk Woo Lee, Min Joo Kim, Se Kon Kim, Gue Tae Chae |
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Chronic Diseases Laboratory, College of Medicine, Catholic University, Seoul, Korea |
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1995 |
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28 |
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93 |
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100 |
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We report a case of erythema nodosum leprosum with various systemic manifestations developed in boderline-lepromatous patient after delivery. A 24-year-old postpartum female presented with several plaques and multiple tender nodules of her trunk and arms, concomitantly with high fever, edema of face, hands, and feet, neuralgia of both limbs, and polyarthralgia Skin slit smear for acid-fast bacilli showed 3+BI and 10% MI, and lepromin test was negative. Histopathologic examination reveraled several patch granulomas composed of lymphocytes, epitheliold cells, and foamy macrophages in the dermis of skin biopsy section, and nerve biopsy section showed endoneurial disorganization and perineurial thickening with lymphocytes and epithelioid cells infiltration and fibrosis. Both of the skin and nerve sections revealed many acid-fast bacilli on Fite-Farraco stain. DNA-PCR with DNA extracts from skin biopsy specimen revealed M. leprae specific 360 bp PCR products. Abdominal sonography revealed hepatosplenomegaly and bone scan showed diffuse hyperactivity in periarticular joint space. Electromyography showed polyneuropathy with decreased motor and sensory conduction velocity. |
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