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Á¦¸ñ The Assessment of MDT Implemented In The Leprosy Mission Jesus Hospital in Korea
ÀúÀÚ Nan Hee Kim, Hyeon Ju Jung, Do Won Kim, and Sang Lip Chung ¼Ò¼Ó The Leprosy Mission, Jesus Hospital, Taegu, Korea, Department of Dematology, Kyungpook national University School of Medicine, Taegu, Korea
³âµµ 1993 ±Ç 26
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¿ä¾à In The Leprosy Mission Jesus Hospital(TLM) in Taegu, combined therapy for the
treatment of leprosy patients with DDS and clofazimine(CLO) was started in 1971.
Around 1977, triple therapy of combination of DDS, CLO and rifampicin(RFD)
implemented in some positive multibacillary leprosy(MBL) patients which has been
extended to all positive MBL patients since what is termed multidrug therapy(MDT)
was recommended by WHO in 1982. And MDT for all registered patients has been
implemented since 1985 according to TLM MDT mannual and plan as a modified WHO
MDT. TLM MDT was different in length from WHO MDT for positive MBL patients
extending for 2 years of MDT after negative conversion.
By June 1991, 821 has completed MDT, 430 MBL and 391 PBL and has been under
suveillance for various period as long as 6-7 years up to now. Sept. 1993. We have
observed no evidences of relapse among the patients under surveillance but mild neural
signs and symptoms such as muscle wasting, weakness, or decreased sensation on
hands which were thought to indicate an outcome of a progressive fibrosis of already
inflammed nerves rather to be late reversal reactions in 6 MBL patients with average
duration of 30years of leprosy in the 4¡­5 th year of surveillance after 2 years' MDT.
We are of opinion that MDT, as we have modified and experienced it for relatively
long period of 20 years from 1971 to 1991, has proved successful so far. Through
education most patients understood the concept and purpose of MDT fairly well and
accepted MDT with better compliance and seemed to be pleased with release from
treatment. MDT regimen has proved to have superior therapeutic effect on rapid
clearance of Ml, control ENL and neuralgia with few side effects. Any resistant
phenomenon to MDT has not been observed so far. But allocation of patients to MBL
and PBL seemed to be very important to treat patient sufficiently in lengthy Period
especially for patients with neuralgia and indeterminate patients. With regular
surveillance after adequate and appropriate MDT, leprosy worker should help patients
feel free from leprosy.
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