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제목 |
A Study on Bacterial Index according to Multidrug Therapy in Multibacillary Leprosy Patients |
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저자 |
Koo Weon Jeong, Ee Seok Lim, Hee Suk Lee, Sung Jun Choi, Yong Ma Hah |
소속 |
Institute for Leprosy Research, Korean Leprosy Control Association |
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년도 |
1992 |
권 |
25 |
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호 |
2 |
번호 |
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시작페이지 |
34 |
끝페이지 |
41 |
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첨부 |
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요약 |
A study on the status of Mycobacterium leprae in the skin and nasal smear according
to multidrug therapy (MDT) for 227 multibacillary cases including 127 new cases and
100 relapse cases in the institute was carried out and the following results were
obtained.
1. In 227 multibacillary cases, the average bacterial index(BI) before starting MDT
was 4.81 and average BI at 6 months, 1, 2, 3, 4 and 5 years after starting MDT were
4.46, 4.26, 3.54, 2.92, 2.34 and 1.74 respectively.
So average BI declining rate per year was 0.61.
2. No case became negative in BI until 2 years after starting MDT and 2cases(0.9%)
10cases(4.4%) and 35cases(15.4%) became negative at 3, 4 and Syears after MDT
respectively.
It was considered that the duration of negative conversion depended on BI status
before starting MDT
3. The average BI declining rate per year was 0.61 in 145 male patients and 0.61 in
82 feamle patients. So there was no sexual difference in BI declining.
4. The average BI declining rate per year was 0.60 in 127 new cases 3nd 0.64 in 100
relapse cases. So there was np difference in BI declining between new cases and
relapse cases, too.
5. The average BI declining rate per year was 0.56 in 170 LL patients and 0.80 in 57
BL cases.
So BI declining was faster in BL than LL. This difference may reflect an influence of
cell medicated immunity associated with more having in BL as compared to LL type. |
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내용 |
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