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Á¦¸ñ A Study of Male-Female Ratio in Hansen's Disease (HD) Patients in Korea
ÀúÀÚ Shi Ryong Choi ¼Ò¼Ó Chronic Disease Laboratory, Catholic University Medical College, Seoul, Korea
³âµµ 1992 ±Ç 25
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¿ä¾à According to previous reports, the usually higher male to female ratio of HD patients
is attributed to both environmental and biological factors. In order to confirm the
accuracy to this dictum, we have investigated the M-P ratio of patients in Korea
according to region(1982-1990), age(1982-1987) and types of disease(1982-1987), as well
as in newly registered cases(1973-1990), and observed the trend of ratio change over a
period of years.
1. Geographical distritution
With the exception of Kyonggi and Cheju provinces, all cities and provinces showed a
decreased in the M-F differential. In Pusan and Inchon cities and in North Cholla and
Cheju provinces the M-F ratio is almost equal. And in South Cholla the ratio is lower
than the average ratio(1.43 : 1) in the whole of Korea. However, in the Central
Region(Seoul City, Kyonggi, South & North Chungchong and Kangwon provinces) the
M-F difference in the highest(1.78-1.53 : 1) followed by the South-East Region(Taegu
City, South & North Kyungsang Provinces) where the M-F ratio demonstrates a still
higher prevalence of males(1.58 : 1-1.45 : 1). In the South-West Region(South & North
Cholla), the M-F difference is the lowest(1.40-1.11 : 1).
2. Age distribution
The ratio of M : F cases under 19 years of age was 1.37 : 1 in 1982 decreasing to
1.36 : 1 in 1987. In patients over 60 years of age there was a decrease from 1.51 : 1 in
1982 to 1.40 : 1 in 1987. In the same period of time, the M-F ratio of patients between
20 and 39 years of age decreased from 1.57. 1 to 1.48 : 1, while in patients between 40
and 59 years of age the ratio decreased from 1.61 ; 1 to 1.58 : 1. However though the
difference has progressively decreased there is still a higher prevalence of males.
3. Distribution by the types of disease
Although there has been a decrease in the sex ratio in all types of HD there is a
marked difference in the ratio itself according to types of disease. The M-F ratio of
L+B groups decrease from 1.50 : 1 in 1982 to 1.42 : 1 in 1987, and in the same interval
that of the T+I groups decreased from 1.70 : 1 to 1.60 : 1. The ratio of L+B groups to
T+I groups changed from 1.63 : 1 in 1982 to 1.72 : 1 in 1987, showing an increasing
trend in L+B groups patients.
4. Trend of M-F ratio of newly registered cases
In newly registere cases in 1973. and 1974 the M-F ratio was 2.15 : 1 decreasing
gradually as follows :
from 1975-1979 the ratio decreased to 1.99 : 1
from 1980-1984 the ratio decreased to 1.68 : 1
from 1985-1989 the ratio decreased to 1.56 : 1
further decreasing in 1990 to 1.53 : 1.
These results suggest that, at least in Korea, it is the socioeconomic or cultural and
environmental factors rather than physiological and biological factors which are
responsible for the preponderance of male over female cases of HD. We also conclude
that the male is not inherently more susceptible, nor the female more resistant to the
disease.
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