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제목 |
A STUDY ON THE CHANGE OF SERUM ANTI-PGL-I ANTIBODY ACCORDING TO MULTIDRURG THERAPY IN NEW AND RELAPSED MULTIBACILLARY LEPROSY PATIENTS |
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저자 |
Sung Jun Choi |
소속 |
Institute for Leprosy Research, KLCA |
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년도 |
1988 |
권 |
21 |
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호 |
1 |
번호 |
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시작페이지 |
35 |
끝페이지 |
42 |
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첨부 |
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요약 |
With ELISA test using ND-O-BSA as antigen, anti-PGL-I IgM antibody titers were
followed up serially for 6 months after initiation of multidrug therapy in 14
multibacillary new patients, 9 relapsed patients, and 118 normal healthy control group
and the following results were obtained.
1. The average anti-PGI-I IgM antibody titer of the new cases was 1.14±0.58
(positive rate: 93%), and that of the relapsed cases was 0.82±0.69 (positive rate :
78%), and their values were significantly higher (P<0.001) than that of normal
control group, 0.035±0.072 (positive rate: 3%).
2. The average antibody titer in patients whose BI were 6+ was 1.30, and in each
patients group with BI 5 ,4 , 3 ,2 , that was 0.92, 0.53, 0.79, and 0.51. Like
this the more the bacterial index increases, the more antibody titers increased in
general.
3. Of 7 ENL cases, there were no significant changes of antibody titers in 4 patients,
but in 3 cases antibody titers decreased significantly after development of ENL.
4. All cases except 2 cases showed no decreasing tendency of antibody titers during
the first 6 months after initiation of multidrug therapy. |
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내용 |
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