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제목 |
COMPARATIVE STUDY ON THE EFFECTIVENESS OF TWO DIFFERENTREGIMENS IN THE MULTI-DRUG THERAPY IN LEPROSY.(MDT) |
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저자 |
Hwa Young Kim, Il Do Kim |
소속 |
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년도 |
1987 |
권 |
20 |
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호 |
1 |
번호 |
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시작페이지 |
67 |
끝페이지 |
80 |
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첨부 |
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요약 |
Of total 158 multibacillary leprosy patients, 102 cases were being treated with WHO
regimen (dapsone 100㎎ daily, clofazimine 50㎎ daily and rifampicin 600㎎ monthly,
clofazimine 300㎎ monthly) and 56 cases were being treated with lsoprodian 2 tablets
daily and rifampicin 600㎎ monthly, clofazimine 300㎎ monthly, and the following results
were obtained in the comparative study on the effectiveness of two different regimens.
1. Clinical improvements were observed between 9 months and 12 months of
treatment in two regimens and there is no differences in the clinical improvements in
two regimens.
2. Among the new cases, yearly BI declining rate was show 0.54+ in
WHO regimen group and shown 0.4+ in Isoprodian regimen group.
3. In the frequency of E.N.L. reaction, WHO regimen group showed 36.3% of ENL
frequency rate and Isoprodian regimen group 51.8%.
4. In the side-effects of two groups, WHO regimen group showed skin discoloration
and dryness while Isoprodian soup showed gastrointestinal trouble and liver damage.
5. As a result, WHO regimen is more effective than Isoprodian regimen in the
treatment for leprosy patients with multibacillary type. |
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내용 |
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