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제목 |
A Study of Relapse or Reactivation in Leprosy |
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저자 |
Do Won Kim#, Nan Hee Kim#, Sang Lip Chung## |
소속 |
The Leprosy Misson Jesus Hospital#, Dept. of Dermatology, Kyungpook National University, School of Medicine, Taegu, Korea |
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년도 |
1986 |
권 |
19 |
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호 |
1 |
번호 |
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시작페이지 |
83 |
끝페이지 |
92 |
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첨부 |
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요약 |
A Total of 3441 1eprosy patients were registered at The Leprosy Mission Jesus
Hospital from Jan. 1957 to Aug. 1985. Among them 148 patient s had relapsed or
reactivated clinically and/or bacteriogically.
The authors have reviewed all of the relapsed patients and the results are as follows:
1) 96 of 1523 lepromatous patients(6.3%), 18 of 254 borberline patients(7.1%), 22 of
1089 tuberculoid patients(2.0%), and 12 of 575 indeterminate patients(2.1%) had relapsed
respectively. The mean of the relapse .ate was 4.3%(148/3441).
2) Among 1499 currently registered patients in Aug. 1985, 128 patients had relapsed,
including 97 of 640 L-Patients(15.2%), 26 of 187 B-patients(13.9%), and 5 of 454
T-Patients(1.1%).
3) The first relapsed patients was seen initially in 1967. The rate of relapse has
increased markedly since 1976. Relapse was 3 times more likely in males. The most
common age for relapse was in the 5 th decade.
4) Relapse commonly occurred 5-10 years after conversion to a negative skin smear.
The average interval was 9.6 years.
5) The two main causes of relapse were irregular and/or low dose treatment with
DDS. 16 patients however, relapsed in spite of regular full dose treatment with DDS.
6) Most of the patients with the initial diagnosis of T-or I-leprosy had changed their
classification to L-or B-leprosy before they relapsed; but 2 T-and 3 I-patients relapsed
as T-leprosy.
7) Bacterial relapse without clinical manifestations was observed in 18 patients, and
clinical relapse with a negative skin smear was observed in 13 patients.
8) The most common clinical manifestations of relapse were nodules or macules and
the most prevalent bacterial index ranged from 1.0 to 3. |
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내용 |
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