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제목 |
Hepatotoxity of Prothionamide in Multidrug-Therapy of Leprosy |
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저자 |
Yong Ma Ha |
소속 |
Fatima Hospital |
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년도 |
1985 |
권 |
18 |
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호 |
1 |
번호 |
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시작페이지 |
57 |
끝페이지 |
61 |
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첨부 |
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요약 |
215 cases of new or relapsed leprosy cases were administered prothionamide in
combination with dapsone and refampicin on field wort, and following hepatotoxic effects
wee experienced.
1. 21.9% of total patients revealed hepatotoxic findings.
2. Higher proportion of hepatotoxicity is observed in female patients.
3. Toxicity seems paralell with dosage of prothionamide.
4. Incubation time was 108. 1 days.
5. all of affected cases were recovered spontaneously by cessation of the drug
administration, subjective symptoms subsided within shortterm period and laboratory
findings recovered in all cases within 4 months.
6. Thionamides are possible to administer for leprosy treatment in close observation
and available laboratory facilities. |
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내용 |
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