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Á¦¸ñ The Hepatotocity of Multi-Drug Therapy With Prothionamide for Multibacillary leprosy Patients multidrug Therapy
ÀúÀÚ Seung Chul Lee, Do Il Kim ¼Ò¼Ó Institute for Leprosy Research Korean Leprosy Control Association
³âµµ 1985 ±Ç 18
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¿ä¾à LFT abrlormality was observed in 11 of 58 multibacillary leprosy patients treated with
combinations of isoprodian daily adminstered and rifampicin£«clofazlmine monthly
supervised The drug responsible for hepatotoxisity waIn probably prothionamide,
although rifampicin may have been a risk factor. Due to the high incidence of
heptotoxicity it is necessary to perform the liver function test monthly in the initial
1-year course of MDT containing prothionamide.
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