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제목 |
Serum Immunoglobulins and Antibody Responses in Leprosy |
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저자 |
Joo Deuk Kim, Se Jong Kim, Woo Nam Shim |
소속 |
Dept. of Microbiology, Yonsei University College of Medicine World Vision Special Skin Clinic |
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년도 |
1980 |
권 |
13 |
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호 |
1 |
번호 |
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시작페이지 |
57 |
끝페이지 |
63 |
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첨부 |
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요약 |
Serum immunoglobulins(IgG, IgA, IgM) and complement C3 levels were determined in
61 lepromatous leprosy patients (27 fresh cases, 34 old-long-standing-cases), 19
tuberculoid leprosy patients (9 fresh cases, 10 old-long standing-cases), and 20 healthy
controls.
IgG was significantly raised in the both old (long standing) lepromatous and
tuberculoid leprosy patients.
IgA was significantly raised in the both fresh and old lepromatous, and the fresh
tuberculoid leprosy patients.
There were no significant differences in IgM level between the lepromatous leprosy,
the tuberculoid leprosy and the control groups.
Serum complements C3 level was significantly raised only in the old lepromatous
leprosy patients.
In the fresh tuberculoid leprosy-patients, the serum C3 level was significantly lowered.
The serum antibody responses against various mycobacterial antigens (M.
scrofulaceum, M. vaccae, M. gordonae, M. aurum, M. neoaurum, M. nonchromogen) by
agar gel immunodiffusion were studied in lepromatous and tuberculoid patients. All of
these mycobacteria were isolated from soil and subcultured in our laboratory.
One or two precipitating lines of the serum against various mycobacterial antigens
were observed, and the sera from leprosy patients were highly reactive to M. vaccae
and M. scrofulaceum. |
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내용 |
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