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제목 |
The Effects of Rifampicin in the Lepromatous Leprosy (A Preliminary Report) |
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저자 |
Kang Woo Lee(이강우), Won Houh(허원), Shi Ryong Choi(최시룡)# |
소속 |
Dept. of Dermatology, Chronic Disease Laboratory#, Catholic Medical College |
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년도 |
1978 |
권 |
11 |
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호 |
1 |
번호 |
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시작페이지 |
49 |
끝페이지 |
52 |
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첨부 |
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요약 |
Therapeutic effects of rifampicin (300 mg per day), both clinically and
bacteriologically, were observed among 13 lepromatous leprosy patients for 2 to 25
months. It was evident that the fall of BI was gradual and the decrease of MI was
very rapid in all cases. From the results of clinical signs, 6 out of the 13 patients
improved markedly, 2 moderately and 5 slightly. One of the most favourable signs of
clinical improvement was that nodules and raised skin became absorbed and flattened in
a short time. Erythema nodosum leprosum (ENL) and neuritis were seen in 6 out of the
13 patients (moderate ENL 3 cases and mild ENL 3 cases), but the symptoms were
controlled with thalidomide and prednisolone. The patients with ENL required treatment
of a rather prolonged period and showed a tendency of gradual fall in BI and MI during
treatment. There were no significant changes in the complete blood count, platelet count,
SGOT and SGPT except in the lymphocyte count, which slightly increased during the
treatment. No side effects were observed in any cases. |
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내용 |
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